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¡¶ Therapeutic Fc-Fusion Proteins ¡·

Author£º Steven M. Chamow (Editor), Thomas Ryll (Editor), Henry B. Lowman (Editor), Deborah Farson (Editor)


Edited by three pioneers in the field ¨C each with longstanding experience in the biotech industry ¨C and a skilled scientific writer, this is the first book to cover every step in the development and production of immunoglobulin Fc-fusion proteins as therapeutics for human disease: from choosing the right molecular design, to pre-clinical characterization of the purified product, through to batch optimization and quality control for large-scale cGMP production.
    The whole of the second part is devoted to case studies of Fc-fusion proteins that are now commercially successful products. In this section, the authors, several of whom were personally involved in clinical development of the products themselves, detail the product¡¯s background and give insight into issues that were faced and how these issues were overcome during clinical development. This section also includes a chapter on promising new developments for the future.
    An invaluable resource for professionals already working on Fc-fusion proteins and an excellent and thorough introduction for physicians, researchers, and students entering the field.

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